News and Updates
New analysis reveals reduction in valproate prescribing
Prescribing of valproate has reduced significantly following the introduction of a quality improvement programme that promotes safety and patient choice.
New analysis presented to the National Patient Safety Committee shows:
- a 53% reduction in initiation in girls aged 0-12
- a 60% reduction in 13-54 women started on valproate
- a 65% reduction in women re-starting valproate after a break of 6 months
- at least 9 out of 17 mothers have active management of valproate if it was prescribed during pregnancy
- and hospital admissions for women with epilepsy aged 13-54 have not been affected by these changes.
The quality improvement programme follows a recommendation by the PSC in 2023 which was accepted by NHSE in January.
Review finds safety recommendations system ‘untenable’
The current situation on recommendations for safety and quality in healthcare is untenable according to a new review.
The DHSC-commissioned review was published by HSSIB on behalf of a group of ALBs. It concludes that the substantial number of recommendations made to the healthcare system means providers struggle to prioritise and implement recommendations.
It found that the lack of structure around the creation and implementation of recommendations as well as the lack of monitoring of actions means many are not improving patient care while continuing to burden providers.
Some recommendations duplicate or contradict others and most are not costed, which may affect providers’ ability to implement them and means there is a lack of information to support prioritisation decisions. Some may be of limited relevance to certain providers and could promote inequalities by negatively impacting certain patient groups if implemented. There is a lack of monitoring of the actions planned or taken to address recommendations.
Welcoming the report, the PSC said: ‘It is becoming increasingly clear to the public that vital recommendations for urgent changes to be made to keep the public safe are simply not being acted upon, leaving persistent risks unaddressed and patients and staff vulnerable.
‘It is essential that the public can have the confidence that recommendations commissioned from independent safety bodies, reviews and Inquiries are properly co-ordinated and followed up with tangible actions. Patients deserve a healthcare system where safety is a top priority, where lessons are learned, and avoidable harms are removed. It is unacceptable that findings which could prevent harm or injury can be neglected for decades.’
The review recommends further work to look at setting up a repository for recommendations, a monitoring system and a route of escalation for recommendations that are not implemented.
PSC welcomes new guidance on valproate usage by men
Men taking valproate and their partners are being advised to use effective contraception according to new guidance from the MHRA. It recommends that male patients and their partners use effective contraception during valproate treatment and for at least three months after stopping the medication.
It follows a study which reports a possible association between valproate use by men and a small increased risk of a range of neurodevelopmental disorders in their children when compared to men prescribed other medicines for the same conditions (lamotrigine or levetiracetam).
Though the risk is much lower than the risk of neurodevelopmental disorders in children born to mothers who take valproate during pregnancy, and the MHRA has long advised against the use of valproate by women able to have children unless there is a Pregnancy Prevention Programme (PPP) in place, this new advice acknowledges that valproate use in fathers is also associated with risk to children as well.
The full guidance can be found here
New summary of key patient safety surveys
The 2024 edition of Patient Experience in England is now available from Care Opinion.
As well as summarising the key findings from last year’s large scale patient surveys, the report looks at wider research covering issues such as equity and accessibility as well as studies on patient voice and safety. It is available at Patient Experience Library
NHS England launches new primary care patient safety strategy
NHS England has released a new primary care patient safety strategy. Although the National Patient Strategy pertains to all sectors, this new strategy provides specific focus on primary care and sets out national and local commitments. View it at NHS England » The NHS Patient Safety Strategy
The latest blog from the PSC:
Using the Patient Safety Principles to improve culture
All healthcare work sometimes includes making truly difficult decisions, decisions that can have serious consequences for patients and their families, now, or in the future. This stretches from wards to Boards and into every part of the healthcare system. You only need...
The latest guest blog:
’Striking the right balance with antidepressant prescribing’
Antidepressant prescribing is at record levels in England, with around one in five adults receiving these medicines for a range of mental health conditions and chronic pain. Prescriptions have...
The latest blog from the PSC
Using the Patient Safety Principles to improve culture
All healthcare work sometimes includes making truly difficult decisions, decisions that can have serious consequences for patients and their families, now, or in the future. This stretches from wards to Boards and into every part of the healthcare system. You only need...
Implementing Martha’s Rule
As Martha’s Rule is introduced into the health system, colleagues who have pioneered the initiative in the UK and globally outline their experience in a series of blogs.
Demos head Polly Curtis, a member of the Martha’s Rule oversight group, outlines her involvement in the group.
I am the chief executive of Demos, a cross-party think tank that works to put people at the heart of policy making to improve how policy is developed as well as trust in politics. Think tanks sit outside government and are hives of ideas of how to improve the country, so it is…
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